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Low Dosage of Histone H4 Leads to Growth Defects and Morphological Changes in Candida albicans
Chromatin function depends on adequate histone stoichiometry. Alterations in histone dosage affect transcription and chromosome segregation, leading to growth defects and aneuploidies. In the fungal pathogen Candida albicans, aneuploidy formation is associated with antifungal resistance and pathogen...
| Autores principales: | , , , |
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| Formato: | Texto |
| Idioma: | English |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869362/ https://www.ncbi.nlm.nih.gov/pubmed/20498713 http://dx.doi.org/10.1371/journal.pone.0010629 |