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Polarization of the Yeast Pheromone Receptor Requires Its Internalization but Not Actin-dependent Secretion

In the best understood models of eukaryotic directional sensing, chemotactic cells maintain a uniform distribution of surface receptors even when responding to chemical gradients. The yeast pheromone receptor is also uniformly distributed on the plasma membrane of vegetative cells, but pheromone ind...

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Detalles Bibliográficos
Autores principales: Suchkov, Dmitry V., DeFlorio, Reagan, Draper, Edward, Ismael, Amber, Sukumar, Madhushalini, Arkowitz, Robert, Stone, David E.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869379/
https://www.ncbi.nlm.nih.gov/pubmed/20335504
http://dx.doi.org/10.1091/mbc.E09-08-0706