Lack of Humoral Immune Response to the Tetracycline (Tet) Activator in Rats Injected Intracranially with Tet-off rAAV Vectors

The ability to safely control transgene expression from viral vectors is a long-term goal in the gene therapy field. We have previously reported tight regulation of GFP expression in rat brain using a self-regulating tet-off rAAV vector. The immune responses against tet regulatory elements observed...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Ye, Chang, Qin A., Virag, Tamas, West, Neva C., George, David, Castro, Maria G., Bohn, Martha C.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869394/
https://www.ncbi.nlm.nih.gov/pubmed/20164859
http://dx.doi.org/10.1038/gt.2010.6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869394/
https://www.ncbi.nlm.nih.gov/pubmed/20164859
http://dx.doi.org/10.1038/gt.2010.6

Ejemplares similares