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The chromatin remodeler ACF acts as a dimeric motor to space nucleosomes

Evenly spaced nucleosomes directly correlate with condensed chromatin and gene silencing. The ATP-dependent chromatin assembly factor (ACF) forms such structures in vitro and is required for silencing in vivo. ACF generates and maintains nucleosome spacing by constantly moving a nucleosome towards t...

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Detalles Bibliográficos
Autores principales: Racki, Lisa R., Yang, Janet G., Naber, Nariman, Partensky, Peretz D., Acevedo, Ashley, Purcell, Thomas J., Cooke, Roger, Cheng, Yifan, Narlikar, Geeta J.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869534/
https://www.ncbi.nlm.nih.gov/pubmed/20033039
http://dx.doi.org/10.1038/nature08621