Comparison of Extensive Protein Fractionation and Repetitive LC-MS/MS Analyses on Depth of Analysis for Complex Proteomes

[Image: see text] In-depth, reproducible coverage of complex proteomes is challenging because the complexity of tryptic digests subjected to LC-MS/MS analysis frequently exceeds mass spectrometer analytical capacity, which results in undersampling of data. In this study, we used cancer cell lysates...

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Detalles Bibliográficos
Autores principales: Wang, Huan, Chang-Wong, Tony, Tang, Hsin-Yao, Speicher, David W.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2870931/
https://www.ncbi.nlm.nih.gov/pubmed/20014860
http://dx.doi.org/10.1021/pr900927y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2870931/
https://www.ncbi.nlm.nih.gov/pubmed/20014860
http://dx.doi.org/10.1021/pr900927y

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