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Synthetic incorporation of Nile Blue into DNA using 2′-deoxyriboside substitutes: Representative comparison of (R)- and (S)-aminopropanediol as an acyclic linker

The Nile Blue chromophore was incorporated into oligonucleotides using “click” chemistry for the postsynthetic modification of oligonucleotides. These were synthesized using DNA building block 3 bearing an alkyne group and reacted with the azide 4. (R)-3-amino-1,2-propanediol was applied as the link...

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Detalles Bibliográficos
Autores principales: Lachmann, Daniel, Berndl, Sina, Wolfbeis, Otto S, Wagenknecht, Hans-Achim
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871008/
https://www.ncbi.nlm.nih.gov/pubmed/20485595
http://dx.doi.org/10.3762/bjoc.6.13