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The Yeast PUF Protein Puf5 Has Pop2-Independent Roles in Response to DNA Replication Stress
PUFs are RNA binding proteins that promote mRNA deadenylation and decay and inhibit translation. Yeast Puf5 is the prototype for studying PUF-dependent gene repression. Puf5 binds to the Pop2 subunit of the Ccr4-Pop2-NOT mRNA deadenylase, recruiting the deadenylase and associated translational repre...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871046/ https://www.ncbi.nlm.nih.gov/pubmed/20498834 http://dx.doi.org/10.1371/journal.pone.0010651 |