Deep Sequencing of Human Nuclear and Cytoplasmic Small RNAs Reveals an Unexpectedly Complex Subcellular Distribution of miRNAs and tRNA 3′ Trailers

BACKGROUND: MicroRNAs (miRNAs) are ∼22-nt small non-coding regulatory RNAs that have generally been considered to regulate gene expression at the post-transcriptional level in the cytoplasm. However, recent studies have reported that some miRNAs localize to and function in the nucleus. METHODOLOGY/P...

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Detalles Bibliográficos
Autores principales: Liao, Jian-You, Ma, Li-Ming, Guo, Yan-Hua, Zhang, Yu-Chan, Zhou, Hui, Shao, Peng, Chen, Yue-Qin, Qu, Liang-Hu
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871053/
https://www.ncbi.nlm.nih.gov/pubmed/20498841
http://dx.doi.org/10.1371/journal.pone.0010563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871053/
https://www.ncbi.nlm.nih.gov/pubmed/20498841
http://dx.doi.org/10.1371/journal.pone.0010563

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