A Novel PARP Inhibitor L-2286 in a Rat Model of Impact Acceleration Head Injury: An Immunohistochemical and Behavioral Study

We examined the neuro/axono-protective potential of a novel poly (ADP-ribose) polymerase (PARP) inhibitor L-2286 in a rat impact acceleration brain injury model. Male Wistar rats (n = 70) weighing 300–350 grams were used to determine the most effective intracerebroventricular (i.c.v.) dose of L-2286...

Descripción completa

Detalles Bibliográficos
Autores principales: Kövesdi, Erzsébet, Bukovics, Péter, Besson, Valérie, Nyirádi, József, Lückl, János, Pál, József, Sümegi, Balázs, Dóczi, Tamás, Hernádi, István, Büki, András
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871115/
https://www.ncbi.nlm.nih.gov/pubmed/20480019
http://dx.doi.org/10.3390/ijms11041253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871115/
https://www.ncbi.nlm.nih.gov/pubmed/20480019
http://dx.doi.org/10.3390/ijms11041253

Ejemplares similares