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A Novel PARP Inhibitor L-2286 in a Rat Model of Impact Acceleration Head Injury: An Immunohistochemical and Behavioral Study

We examined the neuro/axono-protective potential of a novel poly (ADP-ribose) polymerase (PARP) inhibitor L-2286 in a rat impact acceleration brain injury model. Male Wistar rats (n = 70) weighing 300–350 grams were used to determine the most effective intracerebroventricular (i.c.v.) dose of L-2286...

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Detalles Bibliográficos
Autores principales:	Kövesdi, Erzsébet, Bukovics, Péter, Besson, Valérie, Nyirádi, József, Lückl, János, Pál, József, Sümegi, Balázs, Dóczi, Tamás, Hernádi, István, Büki, András
Formato:	Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871115/ https://www.ncbi.nlm.nih.gov/pubmed/20480019 http://dx.doi.org/10.3390/ijms11041253

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