Cargando…

Daytime pharmacodynamic and pharmacokinetic evaluation of low-dose sublingual transmucosal zolpidem hemitartrate

OBJECTIVES: Buffered low-dose sublingual transmucosal zolpidem lozenge hemitartrate (ST zolpidem) is being developed for the treatment of middle-of-the-night insomnia. The objective of this double-blind placebo-controlled cross-over study (n = 24) was to evaluate the pharmacokinetics (PK) and daytim...

Descripción completa

Detalles Bibliográficos
Autores principales: Roth, Thomas, Mayleben, David, Corser, Bruce C, Singh, Nikhilesh N
Formato: Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871168/
https://www.ncbi.nlm.nih.gov/pubmed/17907263
http://dx.doi.org/10.1002/hup.884