AKAR2-AKAP12 fusion protein "biosenses" dynamic phosphorylation and localization of a GPCR-based scaffold

BACKGROUND: The cAMP-dependent protein kinase A (PKA) plays a pivotal role in virtually all cells, there being a multitude of important target molecules that are substrates for PKA in cell signaling. The spatial-temporal dynamics of PKA activation in living cells has been made accessible by the deve...

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Detalles Bibliográficos
Autores principales: Tao, Jiangchuan, Wang, Hsien-yu, Malbon, Craig C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871262/
https://www.ncbi.nlm.nih.gov/pubmed/20412577
http://dx.doi.org/10.1186/1750-2187-5-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871262/
https://www.ncbi.nlm.nih.gov/pubmed/20412577
http://dx.doi.org/10.1186/1750-2187-5-3

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