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Synthesis of (3R,5R)-harzialactone A and its (3R,5S)-isomer

The total synthesis of (3R,5R)-harzialactone A (1) and its (3R,5S)-isomer (2) is described. Epoxide opening with thioacetal and diastereoselective reductions are used as key reactions.

Detalles Bibliográficos
Autores principales: Sabitha, Gowravaram, Srinivas, Rangavajjula, Das, Sukant K, Yadav, Jhillu S
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871370/
https://www.ncbi.nlm.nih.gov/pubmed/20485590
http://dx.doi.org/10.3762/bjoc.6.8