Multiplex N-terminome Analysis of MMP-2 and MMP-9 Substrate Degradomes by iTRAQ-TAILS Quantitative Proteomics

Proteolysis is a major protein posttranslational modification that, by altering protein structure, affects protein function and, by truncating the protein sequence, alters peptide signatures of proteins analyzed by proteomics. To identify such modified and shortened protease-generated neo-N-termini...

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Detalles Bibliográficos
Autores principales: Prudova, Anna, auf dem Keller, Ulrich, Butler, Georgina S., Overall, Christopher M.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2010
Materias:
Proteolysis/Degradomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871422/
https://www.ncbi.nlm.nih.gov/pubmed/20305284
http://dx.doi.org/10.1074/mcp.M000050-MCP201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871422/
https://www.ncbi.nlm.nih.gov/pubmed/20305284
http://dx.doi.org/10.1074/mcp.M000050-MCP201

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