In Planta Protein Sialylation through Overexpression of the Respective Mammalian Pathway

Many therapeutic proteins are glycosylated and require terminal sialylation to attain full biological activity. Current manufacturing methods based on mammalian cell culture allow only limited control of this important posttranslational modification, which may lead to the generation of products with...

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Detalles Bibliográficos
Autores principales: Castilho, Alexandra, Strasser, Richard, Stadlmann, Johannes, Grass, Josephine, Jez, Jakub, Gattinger, Pia, Kunert, Renate, Quendler, Heribert, Pabst, Martin, Leonard, Renaud, Altmann, Friedrich, Steinkellner, Herta
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Glycobiology and Extracellular Matrices
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871460/
https://www.ncbi.nlm.nih.gov/pubmed/20305285
http://dx.doi.org/10.1074/jbc.M109.088401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871460/
https://www.ncbi.nlm.nih.gov/pubmed/20305285
http://dx.doi.org/10.1074/jbc.M109.088401

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