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Explaining the Atypical Reaction Profiles of Heme Enzymes with a Novel Mechanistic Hypothesis and Kinetic Treatment

Many heme enzymes show remarkable versatility and atypical kinetics. The fungal extracellular enzyme chloroperoxidase (CPO) characterizes a variety of one and two electron redox reactions in the presence of hydroperoxides. A structural counterpart, found in mammalian microsomal cytochrome P450 (CYP)...

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Detalles Bibliográficos
Autores principales: Manoj, Kelath Murali, Baburaj, Arun, Ephraim, Binoy, Pappachan, Febin, Maviliparambathu, Pravitha Parapurathu, Vijayan, Umesh K., Narayanan, Sivaprasad Valiyaveettil, Periasamy, Kalaiselvi, George, Ebi Ashley, Mathew, Lazar T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871781/
https://www.ncbi.nlm.nih.gov/pubmed/20498847
http://dx.doi.org/10.1371/journal.pone.0010601