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Sphingosine Kinase-1 (SphK-1) Regulates Mycobacterium smegmatis Infection in Macrophages

Sphingosine kinase-1 is known to mediate Mycobacterium smegmatis induced inflammatory responses in macrophages, but its role in controlling infection has not been reported to date. We aimed to unravel the significance of SphK-1 in controlling M. smegmatis infection in RAW 264.7 macrophages. Our resu...

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Detalles Bibliográficos
Autores principales: Prakash, Hridayesh, Lüth, Anja, Grinkina, Natalia, Holzer, Daniela, Wadgaonkar, Raj, Gonzalez, Alexis Perez, Anes, Elsa, Kleuser, Burkhard
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871783/
https://www.ncbi.nlm.nih.gov/pubmed/20498849
http://dx.doi.org/10.1371/journal.pone.0010657