Potent Cardioprotective Effect of the 4-Anilinoquinazoline Derivative PD153035: Involvement of Mitochondrial K(ATP) Channel Activation

BACKGROUND: The aim of the present study was to evaluate the protective effects of the 4-anilinoquinazoline derivative PD153035 on cardiac ischemia/reperfusion and mitochondrial function. METHODOLOGY/PRINCIPAL FINDINGS: Perfused rat hearts and cardiac HL-1 cells were used to determine cardioprotecti...

Descripción completa

Detalles Bibliográficos
Autores principales: Cavalheiro, Renata A., Marin, Rodrigo M., Rocco, Silvana A., Cerqueira, Fernanda M., Caldeira da Silva, Camille C., Rittner, Roberto, Kowaltowski, Alicia J., Vercesi, Anibal E., Franchini, Kleber G., Castilho, Roger F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871796/
https://www.ncbi.nlm.nih.gov/pubmed/20498724
http://dx.doi.org/10.1371/journal.pone.0010666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871796/
https://www.ncbi.nlm.nih.gov/pubmed/20498724
http://dx.doi.org/10.1371/journal.pone.0010666

Ejemplares similares