Anticancer Conjugates and Cocktails Based on Methotrexate and Nucleoside Synergism

Conjugates of methotrexate (MTX) and the nucleoside analogs 3-azidodeoxythymidine (AZT), iododeoxyuridine (IUdR) and dideoxycytidine (ddC) linked using poly(ethyleneglycol) are presented. In vitro cytotoxicity assays of the conjugates against drug resistant ovarian cell line A2780/AD are preformed a...

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Detalles Bibliográficos
Autores principales: Vortherms, Anthony R., Dang, Hester N., Doyle, Robert P.
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2009
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872594/
https://www.ncbi.nlm.nih.gov/pubmed/20689607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872594/
https://www.ncbi.nlm.nih.gov/pubmed/20689607

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