Tradeoff between enzyme and metabolite efficiency maintains metabolic homeostasis upon perturbations in enzyme capacity

What is the relationship between enzymes and metabolites, the two major constituents of metabolic networks? We propose three alternative relationships between enzyme capacity and metabolite concentration alterations based on a Michaelis–Menten kinetic; that is enzyme capacities, metabolite concentra...

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Detalles Bibliográficos
Autores principales: Fendt, Sarah-Maria, Buescher, Joerg Martin, Rudroff, Florian, Picotti, Paola, Zamboni, Nicola, Sauer, Uwe
Formato: Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872607/
https://www.ncbi.nlm.nih.gov/pubmed/20393576
http://dx.doi.org/10.1038/msb.2010.11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872607/
https://www.ncbi.nlm.nih.gov/pubmed/20393576
http://dx.doi.org/10.1038/msb.2010.11

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