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Pre-dispositions and epigenetic inheritance in the Escherichia coli lactose operon bistable switch

The lactose operon regulation in Escherichia coli is a primary model of phenotypic switching, reminiscent of cell fate determination in higher organisms. Under conditions of bistability, an isogenic cell population partitions into two subpopulations, with the operon's genes turned on or remaini...

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Detalles Bibliográficos
Autores principales: Robert, Lydia, Paul, Gregory, Chen, Yong, Taddei, François, Baigl, Damien, Lindner, Ariel B
Formato: Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872608/
https://www.ncbi.nlm.nih.gov/pubmed/20393577
http://dx.doi.org/10.1038/msb.2010.12