Target mRNA abundance dilutes microRNA and siRNA activity

Post-transcriptional regulation by microRNAs and siRNAs depends not only on characteristics of individual binding sites in target mRNA molecules, but also on system-level properties such as overall molecular concentrations. We hypothesize that an intracellular pool of microRNAs/siRNAs faced with a l...

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Detalles Bibliográficos
Autores principales: Arvey, Aaron, Larsson, Erik, Sander, Chris, Leslie, Christina S, Marks, Debora S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872614/
https://www.ncbi.nlm.nih.gov/pubmed/20404830
http://dx.doi.org/10.1038/msb.2010.24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872614/
https://www.ncbi.nlm.nih.gov/pubmed/20404830
http://dx.doi.org/10.1038/msb.2010.24

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