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Human Variation in Short Regions Predisposed to Deep Evolutionary Conservation

The landscape of the human genome consists of millions of short islands of conservation that are 100% conserved across multiple vertebrate genomes (termed “bricks”), the majority of which are located in noncoding regions. Several hundred thousand bricks are deeply conserved reaching the genomes of a...

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Detalles Bibliográficos
Autores principales: Loots, Gabriela G., Ovcharenko, Ivan
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872621/
https://www.ncbi.nlm.nih.gov/pubmed/20093432
http://dx.doi.org/10.1093/molbev/msq011