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CCTα and CCTδ Chaperonin Subunits Are Essential and Required for Cilia Assembly and Maintenance in Tetrahymena

BACKGROUND: The eukaryotic cytosolic chaperonin CCT is a hetero-oligomeric complex formed by two rings connected back-to-back, each composed of eight distinct subunits (CCTα to CCTζ). CCT complex mediates the folding, of a wide range of newly synthesised proteins including tubulin (α, β and γ) and a...

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Detalles Bibliográficos
Autores principales: Seixas, Cecilia, Cruto, Teresa, Tavares, Alexandra, Gaertig, Jacek, Soares, Helena
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872681/
https://www.ncbi.nlm.nih.gov/pubmed/20502701
http://dx.doi.org/10.1371/journal.pone.0010704