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The Effect of Chronic Candesartan Therapy on the Metabolic Profile and Renal Tissue Cytokine Levels in the Obese Zucker Rat

The effect of candesartan, an angiotensin-II type-1 receptor antagonist, on the metabolic profile and renal inflammation is unclear. We evaluated this relationship by feeding male lean (LZ) and obese (OZ) Zucker rats chow or chow with candesartan (23.5 mg/kg · diet) for 14 weeks (n = 6–8/treatment/b...

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Detalles Bibliográficos
Autores principales: Ecelbarger, Carolyn M., Rash, Arjun, Sinha, Rajesh K., Tiwari, Swasti
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872766/
https://www.ncbi.nlm.nih.gov/pubmed/20490358
http://dx.doi.org/10.1155/2010/841343