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Titration of the plasma effect site equilibrium rate constant of propofol; a link method of 'Concentration-Probability-Time'

BACKGROUND: The plasma effect-site equilibrium rate constant (k(e0)) of propofol has been reported in various pharmacodynamic studies; however, it is not desirable to apply k(e0) for the link with pharmacokinetic models that were separately investigated. Thus, we titrated k(e0) for the pharmacokinet...

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Detalles Bibliográficos
Autores principales: Kim, Jong-Yeop, Park, Sung-Yong, Park, Sun-Kyung, Kim, Jin-Soo, Min, Sang-Kee
Formato: Texto
Lenguaje:English
Publicado: The Korean Society of Anesthesiologists 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872834/
https://www.ncbi.nlm.nih.gov/pubmed/20498770
http://dx.doi.org/10.4097/kjae.2010.58.3.231