Cardioprotection by kappa-opioid receptor agonist U50488H is mediated by opioidergic regulation but not by calcium current modulation

BACKGROUND: Because the κ-opioid receptor (OR) agonist U50488H stimulates opioidergic regulation and inhibits L-type Ca(2+) channels, this study was aimed at assessing the roles of OR and L-type Ca(2+) channels on U50488H-induced cardioprotection. METHODS: Langendorff-perfused rat hearts were subjec...

Descripción completa

Detalles Bibliográficos
Autores principales: Chun, Kook Jin, Jang, Young Ho, Kim, June Hong, Kim, Jun, Park, Yong Hyun
Formato: Texto
Lenguaje:English
Publicado: The Korean Society of Anesthesiologists 2010
Materias:
Experimental Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872865/
https://www.ncbi.nlm.nih.gov/pubmed/20498795
http://dx.doi.org/10.4097/kjae.2010.58.2.162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872865/
https://www.ncbi.nlm.nih.gov/pubmed/20498795
http://dx.doi.org/10.4097/kjae.2010.58.2.162

Ejemplares similares