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Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation

The Cdc42 guanosine triphosphatase is essential for cell polarization in several organisms and in vitro for the organization of polarized epithelial cysts. A long-standing question concerns the identity of the guanine nucleotide exchange factor (GEF) that controls this process. Using Madin–Darby can...

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Detalles Bibliográficos
Autores principales: Qin, Yi, Meisen, Walter H., Hao, Yi, Macara, Ian G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872902/
https://www.ncbi.nlm.nih.gov/pubmed/20479467
http://dx.doi.org/10.1083/jcb.201002097