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Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage

Mutations in the transcription factor SOX10 cause neurocristopathies, including Waardenburg-Hirschsprung syndrome and peripheral neuropathies in humans. This is partly attributed to a requirement for Sox10 in early neural crest for survival, maintenance of pluripotency, and specification to several...

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Detalles Bibliográficos
Autores principales: Finzsch, Markus, Schreiner, Silke, Kichko, Tatjana, Reeh, Peter, Tamm, Ernst R., Bösl, Michael R., Meijer, Dies, Wegner, Michael
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872908/
https://www.ncbi.nlm.nih.gov/pubmed/20457761
http://dx.doi.org/10.1083/jcb.200912142