Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis

We report the discovery of small molecules that target the Rho pathway, a central regulator of cytokinesis, the final step in cell division. We have developed a method to target a small molecule screen towards a specific pathway, which should be widely applicable to study any signaling pathway. In a...

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Detalles Bibliográficos
Autores principales: Castoreno, Adam B., Smurnyy, Yegor, Torres, Angelica D., Vokes, Martha S., Jones, Thouis R., Carpenter, Anne E., Eggert, Ulrike S.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873065/
https://www.ncbi.nlm.nih.gov/pubmed/20436488
http://dx.doi.org/10.1038/nchembio.363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873065/
https://www.ncbi.nlm.nih.gov/pubmed/20436488
http://dx.doi.org/10.1038/nchembio.363

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