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Adenoviral Targeting of Gene Expression to Tumors

Using biochemical, imaging and histological methods, we employed transcriptional targeting to increase the specificity of tumor gene expression in vivo for intravenously administered recombinant adenovirus vectors. Surprisingly, the relative specificity of tumor expression in comparison to other tis...

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Detalles Bibliográficos
Autores principales: Hogg, Richard T., Garcia, Joseph A., Gerard, Robert D.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873120/
https://www.ncbi.nlm.nih.gov/pubmed/20139924
http://dx.doi.org/10.1038/cgt.2010.1