Tetrabenazine is neuroprotective in Huntington's disease mice

BACKGROUND: Huntington's disease (HD) is a neurodegenerative disorder caused by a polyglutamine (polyQ) expansion in Huntingtin protein (Htt). PolyQ expansion in Httexp causes selective degeneration of striatal medium spiny neurons (MSN) in HD patients. A number of previous studies suggested th...

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Detalles Bibliográficos
Autores principales: Wang, Hongyu, Chen, Xi, Li, Yuemei, Tang, Tie-Shan, Bezprozvanny, Ilya
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873255/
https://www.ncbi.nlm.nih.gov/pubmed/20420689
http://dx.doi.org/10.1186/1750-1326-5-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873255/
https://www.ncbi.nlm.nih.gov/pubmed/20420689
http://dx.doi.org/10.1186/1750-1326-5-18

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