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Telomere Lengths, Pulmonary Fibrosis and Telomerase (TERT) Mutations

BACKGROUND: Telomerase is an enzyme that catalyzes the addition of nucleotides on the ends of chromosomes. Rare loss of function mutations in the gene that encodes the protein component of telomerase (TERT) have been described in patients with idiopathic pulmonary fibrosis (IPF). Here we examine the...

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Detalles Bibliográficos
Autores principales: Diaz de Leon, Alberto, Cronkhite, Jennifer T., Katzenstein, Anna-Luise A., Godwin, J. David, Raghu, Ganesh, Glazer, Craig S., Rosenblatt, Randall L., Girod, Carlos E., Garrity, Edward R., Xing, Chao, Garcia, Christine Kim
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873288/
https://www.ncbi.nlm.nih.gov/pubmed/20502709
http://dx.doi.org/10.1371/journal.pone.0010680