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A Helix Replacement Mechanism Directs Metavinculin Functions

Cells require distinct adhesion complexes to form contacts with their neighbors or the extracellular matrix, and vinculin links these complexes to the actin cytoskeleton. Metavinculin, an isoform of vinculin that harbors a unique 68-residue insert in its tail domain, has distinct actin bundling and...

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Detalles Bibliográficos
Autores principales: Rangarajan, Erumbi S., Lee, Jun Hyuck, Yogesha, S. D., Izard, Tina
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873289/
https://www.ncbi.nlm.nih.gov/pubmed/20502710
http://dx.doi.org/10.1371/journal.pone.0010679