Nucleoside Drugs Induce Cellular Differentiation by Caspase-Dependent Degradation of Stem Cell Factors

BACKGROUND: Stem cell characteristics are an important feature of human cancer cells and play a major role in the therapy resistance of tumours. Strategies to target cancer stem cells are thus of major importance for cancer therapy. Differentiation therapy by nucleoside drugs represents an attractiv...

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Detalles Bibliográficos
Autores principales: Musch, Tanja, Öz, Yuva, Lyko, Frank, Breiling, Achim
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873290/
https://www.ncbi.nlm.nih.gov/pubmed/20502711
http://dx.doi.org/10.1371/journal.pone.0010726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873290/
https://www.ncbi.nlm.nih.gov/pubmed/20502711
http://dx.doi.org/10.1371/journal.pone.0010726

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