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A formal model for analyzing drug combination effects and its application in TNF-α-induced NFκB pathway

BACKGROUND: Drug combination therapy is commonly used in clinical practice. Many methods including Bliss independence method have been proposed for drug combination design based on simulations models or experiments. Although Bliss independence method can help to solve the drug combination design pro...

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Detalles Bibliográficos
Autores principales: Yan, Han, Zhang, Bo, Li, Shao, Zhao, Qianchuan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873319/
https://www.ncbi.nlm.nih.gov/pubmed/20416113
http://dx.doi.org/10.1186/1752-0509-4-50