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A formal model for analyzing drug combination effects and its application in TNF-α-induced NFκB pathway
BACKGROUND: Drug combination therapy is commonly used in clinical practice. Many methods including Bliss independence method have been proposed for drug combination design based on simulations models or experiments. Although Bliss independence method can help to solve the drug combination design pro...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873319/ https://www.ncbi.nlm.nih.gov/pubmed/20416113 http://dx.doi.org/10.1186/1752-0509-4-50 |