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MyD88-dependent and independent pathways of Toll-Like Receptors are engaged in biological activity of Triptolide in ligand-stimulated macrophages

BACKGROUND: Triptolide is a diterpene triepoxide from the Chinese medicinal plant Tripterygium wilfordii Hook F., with known anti-inflammatory, immunosuppressive and anti-cancer properties. RESULTS: Here we report the expression profile of immune signaling genes modulated by triptolide in LPS induce...

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Detalles Bibliográficos
Autores principales: Premkumar, Vummidigiridhar, Dey, Moul, Dorn, Ruth, Raskin, Ilya
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873377/
https://www.ncbi.nlm.nih.gov/pubmed/20385024
http://dx.doi.org/10.1186/1472-6769-10-3