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Potent inhibition of tumoral hypoxia-inducible factor 1α by albendazole

BACKGROUND: Emerging reports suggest resistance, increased tumor invasiveness and metastasis arising from treatment with drugs targeting vascular endothelial growth factor (VEGF). It is believed that increased tumoral hypoxia plays a prominent role in the development of these phenomena. Inhibition o...

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Detalles Bibliográficos
Autores principales: Pourgholami, Mohammad H, Cai, Zhao Y, Badar, Samina, Wangoo, Kiran, Poruchynsky, Marianne S, Morris, David L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873385/
https://www.ncbi.nlm.nih.gov/pubmed/20398289
http://dx.doi.org/10.1186/1471-2407-10-143