Why Functional Pre-Erythrocytic and Bloodstage Malaria Vaccines Fail: A Meta-Analysis of Fully Protective Immunizations and Novel Immunological Model

BACKGROUND: Clinically protective malaria vaccines consistently fail to protect adults and children in endemic settings, and at best only partially protect infants. METHODOLOGY/PRINCIPAL FINDINGS: We identify and evaluate 1916 immunization studies between 1965-February 2010, and exclude partially or...

Descripción completa

Detalles Bibliográficos
Autores principales: Guilbride, D. Lys, Gawlinski, Pawel, Guilbride, Patrick D. L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873430/
https://www.ncbi.nlm.nih.gov/pubmed/20502667
http://dx.doi.org/10.1371/journal.pone.0010685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873430/
https://www.ncbi.nlm.nih.gov/pubmed/20502667
http://dx.doi.org/10.1371/journal.pone.0010685

Ejemplares similares