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Why Functional Pre-Erythrocytic and Bloodstage Malaria Vaccines Fail: A Meta-Analysis of Fully Protective Immunizations and Novel Immunological Model
BACKGROUND: Clinically protective malaria vaccines consistently fail to protect adults and children in endemic settings, and at best only partially protect infants. METHODOLOGY/PRINCIPAL FINDINGS: We identify and evaluate 1916 immunization studies between 1965-February 2010, and exclude partially or...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873430/ https://www.ncbi.nlm.nih.gov/pubmed/20502667 http://dx.doi.org/10.1371/journal.pone.0010685 |