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Genome-wide in silico screen for CCCH-type zinc finger proteins of Trypanosoma brucei, Trypanosoma cruzi and Leishmania major

BACKGROUND: CCCH type zinc finger proteins are RNA binding proteins with regulatory functions at all stages of mRNA metabolism. The best-characterized member, tritetraproline (TTP), binds to AU rich elements in 3' UTRs of unstable mRNAs, mediating their degradation. In kinetoplastids, CCCH type...

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Detalles Bibliográficos
Autores principales: Kramer, Susanne, Kimblin, Nicola C, Carrington, Mark
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873481/
https://www.ncbi.nlm.nih.gov/pubmed/20444260
http://dx.doi.org/10.1186/1471-2164-11-283