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Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin inhibits the proliferation of ARPE-19 cells

BACKGROUND: The antiproliferative effect of the Hsp90 inhibitor 17-AAG (17-allylamino-17-demethoxygeldanamycin) on human retinal pigment epithelial cells is investigated. METHODS: MTT and flow cytometry were used to study the antiproliferative effects of the 17-AAG treatment of ARPE-19 cells. 2D gel...

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Detalles Bibliográficos
Autores principales: Yao, Jia-Qi, Liu, Qing-Huai, Chen, Xi, Yang, Qin, Xu, Zhi-Yang, Hu, Fan, Wang, Lin, Li, Jian-Min
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873497/
https://www.ncbi.nlm.nih.gov/pubmed/20416086
http://dx.doi.org/10.1186/1423-0127-17-30