Modulation of the virus-receptor interaction by mutations in the V5 loop of feline immunodeficiency virus (FIV) following in vivo escape from neutralising antibody

BACKGROUND: In the acute phase of infection with feline immunodeficiency virus (FIV), the virus targets activated CD4+ T cells by utilising CD134 (OX40) as a primary attachment receptor and CXCR4 as a co-receptor. The nature of the virus-receptor interaction varies between isolates; strains such as...

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Detalles Bibliográficos
Autores principales: Willett, Brian J, Kraase, Martin, Logan, Nicola, McMonagle, Elizabeth L, Samman, Ayman, Hosie, Margaret J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873508/
https://www.ncbi.nlm.nih.gov/pubmed/20420700
http://dx.doi.org/10.1186/1742-4690-7-38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873508/
https://www.ncbi.nlm.nih.gov/pubmed/20420700
http://dx.doi.org/10.1186/1742-4690-7-38

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