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Properties and identification of antibiotic drug targets

BACKGROUND: We analysed 48 non-redundant antibiotic target proteins from all bacteria, 22 antibiotic target proteins from E. coli only and 4243 non-drug targets from E. coli to identify differences in their properties and to predict new potential drug targets. RESULTS: When compared to non-targets,...

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Detalles Bibliográficos
Autores principales: Bakheet, Tala M, Doig, Andrew J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873537/
https://www.ncbi.nlm.nih.gov/pubmed/20406434
http://dx.doi.org/10.1186/1471-2105-11-195