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Astrocytic expression of Parkinson's disease-related A53T α-synuclein causes neurodegeneration in mice
BACKGROUND: Parkinson's disease (PD) is the most common movement disorder. While neuronal deposition of α-synuclein serves as a pathological hallmark of PD and Dementia with Lewy Bodies, α-synuclein-positive protein aggregates are also present in astrocytes. The pathological consequence of astr...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873589/ https://www.ncbi.nlm.nih.gov/pubmed/20409326 http://dx.doi.org/10.1186/1756-6606-3-12 |