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Bax Inhibitor-1 down-regulation in the progression of chronic liver diseases

BACKGROUND: Bax inhibitor-1 (BI-1) is an evolutionary conserved endoplasmic reticulum protein that, when overexpressed in mammalian cells, suppresses the apoptosis induced by Bax, a pro-apoptotic member of the Bcl-2 family. The aims of this study were: (1) to clarify the role of intrinsic anti- and...

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Detalles Bibliográficos
Autores principales: Kotsafti, Andromachi, Farinati, Fabio, Cardin, Romilda, Burra, Patrizia, Bortolami, Marina
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873598/
https://www.ncbi.nlm.nih.gov/pubmed/20359348
http://dx.doi.org/10.1186/1471-230X-10-35