Role of PKG-L-type calcium channels in the antinociceptive effect of intrathecal sildenafil

Sildenafil increases the cyclic guanosine monophosphate (cGMP) by inhibition of a phosphodiesterase 5, thereby leading to an antinociceptive effect. The increased cGMP may exert the effect on an L-type calcium channel through the activation of protein kinase G (PKG). The purpose of this study was to...

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Detalles Bibliográficos
Autores principales: Kim, Woong Mo, Yoon, Myung Ha, Cui, Jin Hua
Formato: Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873808/
https://www.ncbi.nlm.nih.gov/pubmed/20458149
http://dx.doi.org/10.4142/jvs.2010.11.2.103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873808/
https://www.ncbi.nlm.nih.gov/pubmed/20458149
http://dx.doi.org/10.4142/jvs.2010.11.2.103

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