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FACT Prevents the Accumulation of Free Histones Evicted from Transcribed Chromatin and a Subsequent Cell Cycle Delay in G1

The FACT complex participates in chromatin assembly and disassembly during transcription elongation. The yeast mutants affected in the SPT16 gene, which encodes one of the FACT subunits, alter the expression of G1 cyclins and exhibit defects in the G1/S transition. Here we show that the dysfunction...

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Detalles Bibliográficos
Autores principales: Morillo-Huesca, Macarena, Maya, Douglas, Muñoz-Centeno, Mari Cruz, Singh, Rakesh Kumar, Oreal, Vincent, Reddy, Gajjalaiahvari Ugander, Liang, Dun, Géli, Vincent, Gunjan, Akash, Chávez, Sebastián
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873916/
https://www.ncbi.nlm.nih.gov/pubmed/20502685
http://dx.doi.org/10.1371/journal.pgen.1000964