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Caenorhabditis elegans SMA-10/LRIG Is a Conserved Transmembrane Protein that Enhances Bone Morphogenetic Protein Signaling

Bone morphogenetic protein (BMP) pathways control an array of developmental and homeostatic events, and must themselves be exquisitely controlled. Here, we identify Caenorhabditis elegans SMA-10 as a positive extracellular regulator of BMP–like receptor signaling. SMA-10 acts genetically in a BMP–li...

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Detalles Bibliográficos
Autores principales: Gumienny, Tina L., MacNeil, Lesley, Zimmerman, Cole M., Wang, Huang, Chin, Lena, Wrana, Jeffrey L., Padgett, Richard W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873917/
https://www.ncbi.nlm.nih.gov/pubmed/20502686
http://dx.doi.org/10.1371/journal.pgen.1000963